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Gracias a las +500 personas que participaron en la encuesta y en la interesante discusión! Al señor por cuestiones $ y presión arterial bordeline le indiqué dosis baja de IECA + BB + ARM. + Estudios etiológicos. ⬇️ #HFmrEF Recomendaciones ACCF/AHA/HFSA 22 y ESC 21
#HFmrEF en el mundo real Paciente de 62 años con miocardiopatia dilatada no coronaria en estudio, en CF II, ecocardiograma con FEVI 45% y diámetros VI 62/46. Sin tratamiento médico, derivado al consultorio para evaluación. Que tratamiento inicia? 🤔 #cardiotwitter
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#HFmrEF en el mundo real Paciente de 62 años con miocardiopatia dilatada no coronaria en estudio, en CF II, ecocardiograma con FEVI 45% y diámetros VI 62/46. Sin tratamiento médico, derivado al consultorio para evaluación. Que tratamiento inicia? 🤔 #cardiotwitter
20% BB+IECA/ARA II
8% BB+IECA/ARA II + ARM
69% BB+IECA/ARA+ ARM + iSGLT2
3% Ningún tratamiento
519 votes • Final results
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Cada vez es más frecuente estos pacientes que se encuentra en n #HFmrEF. Totalmente de acuerdo en bloquear el SRAA, además de agregar ISGLT2. Yo además agregaría diuréticos en caso de congestión. Saludos
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For patients with ischemic MR and #HFpEF, consideration for #revascularization and CAD medical treatment are appropriate. Patients with #HFmrEF and ventricular FMR seem to derive benefit from similar regimen as #GDMT for HFrEF, with most evidence for #BBs, #ARNI/ #ARB, and #MRA
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HFpEFはヘフペフ言うけど、HFmrEFってなんていうの詳しい方、分かるかた?? #循環器 #ヘフペフ #HFmrEF
Delighted to host @scottdsolomon at @MacDeptMed @HamHealthSci @PHRIresearch #Cardiology #GrandRounds on Jun 14 at 8 am EST. He will #DELIVER a fantastic lecture on evidence-based therapies for #HeartFailure with #LVEF > 40%. #GDMT #HFmrEF #HFpEF #ARNI #SGLT2i #RAASi #MRA
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I really want this in 🇦🇷!! #HFA #HFrEF #HFmrEF #HFpEF
Lasix 500mg tablets available in Kuwait. #Congestion is the enemy in heart failure. Do not be afraid!!
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Benefits and evolving insights on #SGLT2i in the spectrum of #LVEF: can we set priorities? Current Guidelines Treatment Recommendations in #HFrEF , #HFmrEF and #HFpEF @lamcardio #HeartFailure2022 @WilfriedMullens @HFA_President @scottdsolomon #HFA_ESC #JACCHF @JACCJournals
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#HeartFailure2022: great expectations. #DELIVER trial included a very large population with #HFmrEF & #HFpEF. @scottdsolomon announced trial has met primary endpoint. Loooking forward to listening to the results ... maybe at #ESCongress 2022? #HFimpEF #HFA_ESC
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DELIVER trial by Scott Salomon DELIVER is the largest, broadest trial in #HFmrEF and #HFpEF . • DELIVER will test the primary outcome in two groups - the full population and those with #LVEF < 60% #HeartFailure2022 @Dr_Manito @osmarperse @JuliaSellerm @sccccardio
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#DELIVER baseline and design by @scottdsolomon DELIVER is the largest, broadest trial in #HFmrEF and #HFpEF . • DELIVER will test the primary outcome in two groups - the full population and those with #LVEF < 60% #HeartFailure2022 @HFA_President @HFSA #JACCHF @escardio
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Replying to @cardiomet_CE
37) So, where were we? Oh yes, trials ➡️ benefit of #SGLT2i's in #T2DM, #chronic #HFrEF, #AHF, & #CKD (the latter not covered in this edition). #SGLT2i has now been tested in #chronic #HFpEF, in #EMPEROR_PRESERVED. Here you can see the trial design (🔓pubmed.ncbi.nlm.nih.gov/3444…)
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Does dapagliflozin deliver? #HFpEF and #HFmrEF are difficult clinical entities and patients have had few txs w/RCT evidence. Excited that #Flozins once again Deliver. ☺️ @ChristosArgyrop @DrMarthaGulati @hswapnil @DrNasrien #Flozinator #Cardioneph #CardioTwitter
ICYMI: Earlier this month, AstraZeneca announced the DELIVER trial met its primary endpoint, w/ dapagliflozin use associated with significant and meaningful reductions in the primary composite endpoint of CV death or worsening heart failure in #HFpEF. ow.ly/YeRg50Jb9Xp
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48) Concluding this #tweetorial, #SGLT2i have now (based on the evidence) 6⃣ indications: #TD2M, #CKD, chronic #HFrEF, chronic #HFmrEF, chronic #HFpEF, & #AHF. This justifies the title of “The statins of 21st century”! #FLOZINATE!
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42) The prespecified subgroup analysis in Primary EP did not show any difference between Diabetic vs non-diabetic patients. The ⬇️of primary #EP was significant both in #HFmrEF and in #HFpEF >50% but not in #HFpEF>60%. The last is a population that needs further study.
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38) #EMPEROR_PRESERVED enrolled nearly 6000 pts with the following characteristics, mean age 71.9, Female: 44.7%, NYHA II: 81%, mean LVEF:54%, #HFmREF 33%, #HFpEF (EF>50%) 33%, #HFpEF (EF>60%) 34%, median #NTproBNP: 950 pg/mL , mean #eGFR: 60 ml/min/m2
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31) #EMPULSE enrolled 530 #AHF pts with these characteristics: #T2DM 45%, median #LVEF: 31%; #HFrEF 66%, #HFmrEF + #HFpEF 33%, median #NTproBNP: 3180 pg/mL, median eGFR 52%, de-novo #AHF 33%, worsening #AHF/ decompensated #CHF 66<%
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